Literature summary for 1.1.1.B40 extracted from

Chandras, C.; Harris, T.E.; Bernal, A.L.; Abayasekara, D.R.; Michael, A.E.
PTGER1 and PTGER2 receptors mediate regulation of progesterone synthesis and type 1 11beta-hydroxysteroid dehydrogenase activity by prostaglandin E2 in human granulosa-lutein cells (2007), J. Endocrinol., 194, 595-602.

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Activating Compound

Activating Compound	Comment	Organism	Structure
prostaglandin E2	stimulation of progesterone production and of 11beta-hydroxysteroid dehydrogenase activity via the prostaglandin E receptor 2-cAMP signalling pathway in luteinizing granulosa cells	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
granulosa cell	luteinizing granulosa cell	Homo sapiens	-

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Release 2023.1 (January 2023)