Application | Comment | Organism |
---|---|---|
medicine | pterygium has an altered metabolism of cholesterol, namely increased LDL-R and HMG-CoA-R mRNAs. Both genes may play important roles in the pathogenesis of pterygium | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
conjunctiva | - |
Homo sapiens | - |
pterygium | primary and reccurent pterygium | Homo sapiens | - |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | mRNA levels of HMG-CoA-R are increased significantly in both primary and recurrent pterygia by 4.2fold and 3.6fold respectively, compared with normal conjunctiva. Concomitantly, there is a significant increase of LDL-R mRNA levels of 4.1fold in primary pterygia and 2.7fold in recurrent pterygium, compared with the control normal conjunctiva | up |