Literature summary for 1.1.1.85 extracted from

Hamajima, Y.; Nagae, T.; Watanabe, N.; Kato-Yamada, Y.; Imai, T.; Kato, C.
Pressure effects on the chimeric 3-isopropylmalate dehydrogenases of the deep-sea piezophilic Shewanella benthica and the atmospheric pressure-adapted Shewanella oneidensis (2014), Biosci. Biotechnol. Biochem., 78, 469-471.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
(2R,3S)-3-isopropylmalate + NAD+	Shewanella oneidensis	-	(2S)-2-isopropyl-3-oxosuccinate + NADH + H+	-	?
(2R,3S)-3-isopropylmalate + NAD+	Shewanella benthica	-	(2S)-2-isopropyl-3-oxosuccinate + NADH + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Shewanella benthica	-	-	-
Shewanella oneidensis	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(2R,3S)-3-isopropylmalate + NAD+	-	Shewanella oneidensis	(2S)-2-isopropyl-3-oxosuccinate + NADH + H+	-	?
(2R,3S)-3-isopropylmalate + NAD+	-	Shewanella benthica	(2S)-2-isopropyl-3-oxosuccinate + NADH + H+	-	?

Synonyms

Synonyms	Comment	Organism
IPMDH	-	Shewanella oneidensis
IPMDH	-	Shewanella benthica

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
50	55	-	Shewanella oneidensis
50	55	-	Shewanella benthica

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Shewanella oneidensis
NAD+	-	Shewanella benthica

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Release 2023.1 (January 2023)