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Literature summary for 1.1.1.85 extracted from

  • Graczer, E.; Konarev, P.V.; Szimler, T.; Bacso, A.; Bodonyi, A.; Svergun, D.I.; Zavodszky, P.; Vas, M.
    Essential role of the metal-ion in the IPM-assisted domain closure of 3-isopropylmalate dehydrogenase (2011), FEBS Lett., 585, 3297-3302.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ required. Only the metal-threo-D-3-isopropylmalate complex, but neither the metal-ion nor the free threo-D-3-isopropylmalate itself, is efficient in stabilizing the native protein conformation. In the absence of metal ion, only a very marginal extent of domain closure takes place Thermus thermophilus

Organism

Organism UniProt Comment Textmining
Thermus thermophilus
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