Literature summary for 1.1.1.85 extracted from

Croft, J.E.; Love, D.R.; Bergquist, P.L.
Expression of leucine genes from an extremely thermophilic bacterium in Escherichia coli (1987), Mol. Gen. Genet., 210, 490-497.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Thermus thermophilus

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-
Salmonella enterica subsp. enterica serovar Typhimurium	-	-	-
Thermus thermophilus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(2R,3S)-3-isopropylmalate + NAD+	-	Salmonella enterica subsp. enterica serovar Typhimurium	2-oxoisocaproate + NADH + H+ + CO2	-	?
(2R,3S)-3-isopropylmalate + NAD+	-	Thermus thermophilus	2-oxoisocaproate + NADH + H+ + CO2	-	?
(2R,3S)-3-isopropylmalate + NAD+	-	Escherichia coli	2-oxoisocaproate + NADH + H+ + CO2	-	?

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Salmonella enterica subsp. enterica serovar Typhimurium
NAD+	-	Thermus thermophilus
NAD+	-	Escherichia coli

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Release 2023.1 (January 2023)