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Literature summary for 1.1.1.8 extracted from

  • Popp, A.; Nguyen, H.T.; Boulahya, K.; Bideaux, C.; Alfenore, S.; Guillouet, S.E.; Nevoigt, E.
    Fermentative production of L-glycerol 3-phosphate utilizing a Saccharomyces cerevisiae strain with an engineered glycerol biosynthetic pathway (2008), Biotechnol. Bioeng., 100, 497-505.
    View publication on PubMed

Application

Application Comment Organism
synthesis fermentative production of L-glycerol 3-phosphate utilizing a Saccharomyces cerevisiae strain with an engineered glycerol biosynthetic pathway (strain with deletions in both genes encoding specific L-G3Pases (GPP1 and GPP2) and multicopy overexpression of L-glycerol 3-phosphate dehydrogenase). Up-scaling the process employs fed-batch fermentation with repeated glucose feeding, plus an aerobic growth phase followed by an anaerobic product accumulation phase. This produces a final product titer of about 325 mg total L-glycerol 3-phosphate per liter of fermentation broth Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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Synonyms

Synonyms Comment Organism
GPD1
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Saccharomyces cerevisiae
L-glycerol 3-phosphate dehydrogenase
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Saccharomyces cerevisiae