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Literature summary for 1.1.1.79 extracted from

  • Genolet, R.; Kersten, S.; Braissant, O.; Mandard, S.; Tan, N.S.; Bucher, P.; Desvergne, B.; Michalik, L.; Wahli, W.
    Promoter rearrangements cause species-specific hepatic regulation of the glyoxylate reductase/hydroxypyruvate reductase gene by the peroxisome proliferator-activated receptor alpha (2005), J. Biol. Chem., 280, 24143-24152.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glyoxylate + NADPH Homo sapiens key enzyme in glyoxylate pathway glycolate + NADP+
-
?
glyoxylate + NADPH Mus musculus key enzyme in glyoxylate pathway. The regulation of the GHPR expression by peroxisome proliferator-activated receptor alpha may contribute to energy homeostasis by modulating the carbon supply for gluconeogenesis glycolate + NADP+
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Mus musculus
-
liver
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glyoxylate + NADPH key enzyme in glyoxylate pathway Homo sapiens glycolate + NADP+
-
?
glyoxylate + NADPH key enzyme in glyoxylate pathway. The regulation of the GHPR expression by peroxisome proliferator-activated receptor alpha may contribute to energy homeostasis by modulating the carbon supply for gluconeogenesis Mus musculus glycolate + NADP+
-
?

Synonyms

Synonyms Comment Organism
glyoxylate reductase/hydroxypyruvate reductase
-
Mus musculus
glyoxylate reductase/hydroxypyruvate reductase
-
Homo sapiens
GRHRP
-
Mus musculus
GRHRP
-
Homo sapiens