Inhibitors | Comment | Organism | Structure |
---|---|---|---|
D,L-1-bromopropan-2-ol | - |
Rattus norvegicus | |
D,L-1-chloropropan-2-ol | - |
Rattus norvegicus | |
D,L-propan-1,2-diol | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
4 | - |
NAD+ | for both enantiomers as substrate | Rattus norvegicus | |
48 | - |
L-1-Aminopropan-2-ol | - |
Rattus norvegicus | |
110 | - |
D-1-aminopropan-2-ol | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-1-aminopropan-2-ol + NAD+ | Rattus norvegicus | - |
aminoacetone + NADH | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0006 | - |
for both enantiomers of 1-aminopropan-2-ol | Rattus norvegicus |
Storage Stability | Organism |
---|---|
-20°C, 0.1 M phosphate buffer, pH 7, 6 days, no loss of activity | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D,L-1-aminopropan-2-ol + NAD+ | at high substrate concentrations both enantiomers utilized at the same rate, at low substrate concentration L-enantiomer preferred over D-enantiomer | Rattus norvegicus | aminoacetone + NADH | - |
? | |
D-1-aminopropan-2-ol + NAD+ | - |
Rattus norvegicus | aminoacetone + NADH + H+ | - |
r | |
L-1-aminopropan-2-ol + NAD+ | - |
Rattus norvegicus | aminoacetone + NADH | - |
? | |
L-1-aminopropan-2-ol + NADP+ | half maximum activity | Rattus norvegicus | aminoacetone + NADPH | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
20 | - |
50% loss of activity after 24 h | Rattus norvegicus |
52 | - |
78% loss of activity within 15 min | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9 | - |
- |
Rattus norvegicus |