Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-[5-(3'-hydroxybiphenyl-3-yl)-2-thienyl]ethanone | 0.001 mM, 10 min, 22% inhibition; 0.001 mM, 10 min, 23% inhibition | Homo sapiens | |
1-[5-(3'-Hydroxybiphenyl-4-yl)-2-thienyl]ethanone | 0.001 mM, 10 min, 10% inhibition; 0.001 mM, 10 min, 38% inhibition | Homo sapiens | |
3'-(1-benzothien-2-yl)biphenyl-3-ol | 0.001 mM, 10 min, 39% inhibition; 0.001 mM, 10 min, 49% inhibition | Homo sapiens | |
3'-(2-thienyl)biphenyl-3-ol | 0.001 mM, 10 min, 40% inhibition; 0.001 mM, 10 min, 48% inhibition | Homo sapiens | |
3'-(5-chloro-2-thienyl)biphenyl-3-ol | 0.001 mM, 10 min, 31% inhibition; 0.001 mM, 10 min, 71% inhibition | Homo sapiens | |
3'-(5-methyl-2-thienyl)biphenyl-3-ol | 0.001 mM, 10 min, 32% inhibition; 0.001 mM, 10 min, 36% inhibition | Homo sapiens | |
3-[2-(2-thienyl)pyridin-4-yl]phenol | 0.001 mM, 10 min, 33% inhibition; 0.001 mM, 10 min, 62% inhibition | Homo sapiens | |
3-[2-(5-chloro-2-thienyl)pyridin-4-yl]phenol | 0.001 mM, 10 min, 39% inhibition; 0.001 mM, 10 min, 63% inhibition | Homo sapiens | |
3-[4-(5-chloro-2-thienyl)pyridin-2-yl]phenol | 0.001 mM, 10 min, 25% inhibition; 0.001 mM, 10 min, 61% inhibition | Homo sapiens | |
3-[5-(5-chloro-2-thienyl)pyridin-3-yl]phenol | 0.001 mM, 10 min, 40% inhibition; 0.001 mM, 10 min, 46% inhibition | Homo sapiens | |
3-[6-(5-chloro-2-thienyl)pyridin-2-yl]phenol | 0.001 mM, 10 min, 21% inhibition; 0.001 mM, 10 min, 40% inhibition | Homo sapiens | |
4'-(2-thienyl)biphenyl-3-ol | 0.001 mM, 10 min, 22% inhibition; 0.001 mM, 10 min, 36% inhibition | Homo sapiens | |
4'-(3-furyl)biphenyl-3-ol | 0.001 mM, 10 min, 17% inhibition | Homo sapiens | |
4'-(3-thienyl)biphenyl-3-ol | 0.001 mM, 10 min, 36% inhibition; 0.001 mM, 10 min, 41% inhibition | Homo sapiens | |
4'-(5-chloro-2-thienyl)biphenyl-3-ol | 0.001 mM, 10 min, 48% inhibition | Homo sapiens | |
4'-(6-methoxypyridin-3-yl)biphenyl-3-ol | 0.001 mM, 10 min, 35% inhibition; 0.001 mM, 10 min, 58% inhibition | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P14061 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
estradiol + NAD+ | - |
Homo sapiens | estrone + NADH + H+ | - |
? | |
estrone + NADH + H+ | - |
Homo sapiens | estradiol + NAD+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
17beta-HSD1 | - |
Homo sapiens |
17beta-HSD2 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00047 | - |
37°C, pH not specified in the publication | Homo sapiens | 3-[2-(5-chloro-2-thienyl)pyridin-4-yl]phenol | |
0.00056 | - |
37°C, pH not specified in the publication | Homo sapiens | 3'-(5-chloro-2-thienyl)biphenyl-3-ol | |
0.00069 | - |
37°C, pH not specified in the publication | Homo sapiens | 4'-(6-methoxypyridin-3-yl)biphenyl-3-ol | |
0.00085 | - |
37°C, pH not specified in the publication | Homo sapiens | 3-[4-(5-chloro-2-thienyl)pyridin-2-yl]phenol | |
0.00102 | - |
37°C, pH not specified in the publication | Homo sapiens | 4'-(5-chloro-2-thienyl)biphenyl-3-ol | |
0.00137 | - |
37°C, pH not specified in the publication | Homo sapiens | 3'-(1-benzothien-2-yl)biphenyl-3-ol | |
0.00139 | - |
37°C, pH not specified in the publication | Homo sapiens | 3-[6-(5-chloro-2-thienyl)pyridin-2-yl]phenol | |
0.00194 | - |
37°C, pH not specified in the publication | Homo sapiens | 3'-(1-benzothien-2-yl)biphenyl-3-ol | |
0.00237 | - |
37°C, pH not specified in the publication | Homo sapiens | 3'-(5-chloro-2-thienyl)biphenyl-3-ol | |
0.00238 | - |
37°C, pH not specified in the publication | Homo sapiens | 3-[2-(5-chloro-2-thienyl)pyridin-4-yl]phenol | |
0.00297 | - |
37°C, pH not specified in the publication | Homo sapiens | 4'-(6-methoxypyridin-3-yl)biphenyl-3-ol | |
0.00364 | - |
37°C, pH not specified in the publication | Homo sapiens | 3-[4-(5-chloro-2-thienyl)pyridin-2-yl]phenol | |
0.00711 | - |
37°C, pH not specified in the publication | Homo sapiens | 3-[6-(5-chloro-2-thienyl)pyridin-2-yl]phenol | |
0.01 | - |
value higher than 0.01, 37°C, pH not specified in the publication | Homo sapiens | 4'-(5-chloro-2-thienyl)biphenyl-3-ol |