KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00003 | - |
estrone | wild-type enzyme | Homo sapiens | |
0.0003 | - |
estrone | mutant enzyme L149V | Homo sapiens | |
0.0043 | - |
dihydrotestosterone | mutant enzyme L149V | Homo sapiens | |
0.0046 | - |
estradiol-17beta | wild-type enzyme | Homo sapiens | |
0.01 | - |
estradiol-17beta | mutant enzyme L149V | Homo sapiens | |
0.0172 | - |
dehydroepiandrosterone | mutant enzyme L149V | Homo sapiens | |
0.033 | - |
dihydrotestosterone | wild-type enzyme | Homo sapiens | |
0.045 | - |
dehydroepiandrosterone | wild-type enzyme | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
placenta | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dehydroepiandrosterone + NADP+ | - |
Homo sapiens | ? | - |
? | |
dihydrotestosterone + NAD(P)H + H+ | - |
Homo sapiens | androstane-3beta,17beta-diol + NAD(P)+ | - |
? | |
estrone + NAD(P)H + H+ | - |
Homo sapiens | estradiol-17beta + NAD(P)+ | - |
r |
Synonyms | Comment | Organism |
---|---|---|
17beta-HSD1 | - |
Homo sapiens |
17beta-hydroxysteroid dehydrogenase types 1 | - |
Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.12 | - |
dehydroepiandrosterone | mutant enzyme L149V | Homo sapiens | |
0.16 | - |
dehydroepiandrosterone | wild-type enzyme | Homo sapiens | |
0.24 | - |
estradiol-17beta | mutant enzyme L149V | Homo sapiens | |
0.26 | - |
estrone | mutant enzyme L149V | Homo sapiens | |
0.33 | - |
dihydrotestosterone | wild-type enzyme | Homo sapiens | |
0.34 | - |
dihydrotestosterone | mutant enzyme L149V | Homo sapiens | |
4.4 | - |
estradiol-17beta | wild-type enzyme | Homo sapiens | |
5.8 | - |
estrone | wild-type enzyme | Homo sapiens |