Inhibitors | Comment | Organism | Structure |
---|---|---|---|
enterodiol | - |
Homo sapiens | |
enterolactone | 0.05 mM, 84% inhibition | Homo sapiens | |
genistein | 0.05 mM, 59% inhibition | Homo sapiens | |
additional information | modulation of local synthesis of estradiol is one potential mechanism through which genistein, enterolactone and enterodiol may protect against breast cancer | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
estrone + NAD(P)H + H+ | Homo sapiens | - |
estradiol + NAD(P)+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MCF-7 cell | modulation of local synthesis of estradiol is one potential mechanism through which genistein, enterolactone and enterodiol may protect against breast cancer | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
estrone + NAD(P)H + H+ | - |
Homo sapiens | estradiol + NAD(P)+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
17beta-HSD type 1 | - |
Homo sapiens |