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Literature summary for 1.1.1.62 extracted from

  • Pelletier, G.; Luu-The, V.; Li, S.; Ren, L.; Labrie, F.
    Localization of 17beta-hydroxysteroid dehydrogenase type 1 mRNA in mouse tissues (2004), J. Mol. Endocrinol., 33, 459-465.
    View publication on PubMed
Search for more literature for 1.1.1.62

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
estrone + NADPH + H+ Mus musculus final step in the synthesis of active estrogens estradiol-17beta + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 isoform 1, 17beta-HSD1
-

Source Tissue

Source Tissue Comment Organism Textmining
intermediate lobe
-
 Mus musculus
-
melanotroph
-
 Mus musculus
-
additional information not detectable in corpora lutea, interstitial cells, anterior and posterior lobes, mammary gland, uterus, vagina, adrenal gland, kidney, liver, brain, and lung Mus musculus
-
ovarian follicle high expression in granulosa cells of growing follicles Mus musculus
-
ovary
-
 Mus musculus
-
prostate only in epithelial cells Mus musculus
-
skin detectable in sebaceous glands, absent in epidermis, stroma, hair follicles and sweat glands Mus musculus
-
testis only in germ cells, absent in seminiferous tubules and Leydig cells Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
estrone + NADPH + H+
-
 Mus musculus estradiol-17beta + NADP+
-
 ?
estrone + NADPH + H+ final step in the synthesis of active estrogens Mus musculus estradiol-17beta + NADP+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Mus musculus