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Literature summary for 1.1.1.62 extracted from
- Site-directed mutagenesis of the putative active site of human 17beta-hydroxysteroid dehydrogenase type 1 (1994), Biochem. J., 304, 289-293.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Spodoptera frugiperda Sf9 cells | Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| H210A/H213A | decreased activity | Homo sapiens |
| H221A | catalytic efficiency is reduced 20fold for oxidative reaction and 11fold for the reductive reaction | Homo sapiens |
| Y155A | decreased activity | Homo sapiens |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
type 1 enzyme | - |
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Release 2023.1 (January 2023)
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