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Literature summary for 1.1.1.62 extracted from

  • Newton, C.J.; Butta, A.; Nicholls, J.; Dowsett, M.
    Oestradiol synthesis from oestrone in malignant breast epithelial cells: studies on a high affinity, 80 kDa form of oestradiol dehydrogenase (1992), J. Steroid Biochem. Mol. Biol., 42, 891-900.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information steroids which inhibit conversion of estrone to estradiol in normal breast tissue fail to do so when added to growing monolayers in the breast cancer cell lines T47D and MCF-7 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
additional information
-
Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
80000
-
T47D breast cancer cells, gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-431 cell
-
Homo sapiens
-
breast cell line
-
Homo sapiens
-
CAOV-3 cell
-
Homo sapiens
-
MCF-7 cell
-
Homo sapiens
-
MCF-7 cell breast cancer cell line MCF-7 Homo sapiens
-
MDA-MB-231 cell
-
Homo sapiens
-
ovarian cancer cell
-
Homo sapiens
-
OVCAR-3 cell
-
Homo sapiens
-
T47D cell
-
Homo sapiens
-
T47D cell T47D breast cancer cell line Homo sapiens
-