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Literature summary for 1.1.1.62 extracted from

  • Malet, C.; Vacca, A.; Kuttenn, F.; Mauvais-Jarvis, P.
    17beta-Estradiol dehydrogenase (E2DH) activity in T47D cells (1991), J. Steroid Biochem. Mol. Biol., 39, 769-775.
    View publication on PubMed
Search for more literature for 1.1.1.62

Activating Compound

Activating Compound Comment Organism Structure
R5020 stimulates conversion of estradiol to estrone in T47D cells in culture Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-431 cell
-
 Homo sapiens
-
breast cell line breast cells, activity is far greater in epithelial cells than in fibroblasts Homo sapiens
-
CAOV-3 cell
-
 Homo sapiens
-
MCF-7 cell
-
 Homo sapiens
-
MDA-MB-231 cell
-
 Homo sapiens
-
ovarian cancer cell
-
 Homo sapiens
-
OVCAR-3 cell
-
 Homo sapiens
-
T47D cell
-
 Homo sapiens
-
T47D cell T47D breast cancer cell line Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
estradiol-17beta + NAD+
-
 Homo sapiens estrone + NADH
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD+ cofactor Homo sapiens