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Literature summary for 1.1.1.53 extracted from

  • Senthilkumaran, B.; Sudhakumari, C.C.; Chang, X.T.; Kobayashi, T.; Oba, Y.; Guan, G.; Yoshiura, Y.; Yoshikuni, M.; Nagahama, Y.
    Ovarian carbonyl reductase-like 20beta-hydroxysteroid dehydrogenase shows distinct surge in messenger RNA expression during natural and gonadotropin-induced meiotic maturation in Nile tilapia (2002), Biol. Reprod., 67, 1080-1086.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Oreochromis niloticus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Oreochromis niloticus the enzyme plays an important role in the meiotic maturation of tilapia gametes ?
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?

Organism

Organism UniProt Comment Textmining
Oreochromis niloticus Q8UVJ2
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-

Source Tissue

Source Tissue Comment Organism Textmining
gill
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Oreochromis niloticus
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ovary expression in ovarian follicles is low from day 0 to day 8 after spawning and is not detectable on day 11. Distinct expression is evident at day 14, the day of spawning Oreochromis niloticus
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testis expressed continually in matire testes but not in immature testes of 30-day-old fish Oreochromis niloticus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
17alpha-hydroxyprogesterone + NADPH + H+ 4.3% of the activity with p-nitrobenzaldehyde Oreochromis niloticus 17alpha,20beta-dihydroxy-4-pregnene-3-one + NADP+
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?
5alpha-dihydrotestosterone + NADPH + H+ 14.4% of the activity with p-nitrobenzaldehyde Oreochromis niloticus 5alpha-androstan-3alpha,17beta-diol + NADP+
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?
5beta-dihydrotestosterone + NADPH 9.2% of the activity with p-nitrobenzaldehyde Oreochromis niloticus 5beta-androstan-3alpha,17beta-diol + NADP+
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?
menadione + NADPH 75% of the activity with p-nitrobenzaldehyde Oreochromis niloticus ?
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?
additional information the enzyme plays an important role in the meiotic maturation of tilapia gametes Oreochromis niloticus ?
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?
p-nitrobenzaldehyde + NADPH
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Oreochromis niloticus p-nitrobenzyl alcohol + NADP+
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?
progesterone + NADPH 2.5% of the activity with p-nitrobenzaldehyde Oreochromis niloticus 20beta-hydroxy-pregn-4-ene-3-one + NADP+
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?

Synonyms

Synonyms Comment Organism
20beta-HSD
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Oreochromis niloticus
carbonyl reductase-like 20beta-hydroxysteroid dehydrogenase
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Oreochromis niloticus