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Literature summary for 1.1.1.51 extracted from

  • Tóth, I.; Szécsi, M.; Julesz, J.; Faredin, I.; Behnke, B.
    In vitro inhibition of testicular delta 5-3 beta-hydroxysteroid dehydrogenase and prostatic 5 alpha-reductase activities in rats and humans by strogen forte extract (1996), Int. Urol. Nephrol., 28, 337-348.
    View publication on PubMed

Application

Application Comment Organism
medicine inhibitor Strogen forte extract can be used for treatment of benign prostatic hyperplasia Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
Strogen forte standardized extract of the plant Sabalis serrulata, 0.212 mg/ml result in 50% enzyme inhibition Homo sapiens
Strogen forte standardized extract of the plant Sabalis serrulata, 0.4 mg/ml result in 50% enzyme inhibition Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-
Rattus norvegicus Wistar
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
testis
-
Homo sapiens
-
testis
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dehydroepiandrosterone + NAD+
-
Homo sapiens 4-androstene-3,17-dione + NADH + H+
-
?
dehydroepiandrosterone + NAD+
-
Rattus norvegicus 4-androstene-3,17-dione + NADH + H+
-
?
dehydroepiandrosterone + NAD+
-
Rattus norvegicus Wistar 4-androstene-3,17-dione + NADH + H+
-
?

Synonyms

Synonyms Comment Organism
DELTA5-3beta-HSD
-
Homo sapiens
DELTA5-3beta-HSD
-
Rattus norvegicus