Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
androst-4-ene-3,17-dione + NADPH | Homo sapiens | - |
testosterone + NADP+ | - |
? | |
androstane-3,17-dione + NADPH | Homo sapiens | - |
dihydrotestosterone + NADP+ | - |
? | |
additional information | Homo sapiens | activity of the enzyme is associated with the mechanism of prostatic regulation by androgens after castration, which is important in prostate cancer | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
prostate cancer cell | cancer and bening hyperplasia, protstaic intraepithelial neoplasia, enzyme distribution, overview | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
determination of serum and tumor tissue concentrations of steroids in prostate cancer patients, overview | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
androst-4-ene-3,17-dione + NADPH | - |
Homo sapiens | testosterone + NADP+ | - |
? | |
androstane-3,17-dione + NADPH | - |
Homo sapiens | dihydrotestosterone + NADP+ | - |
? | |
additional information | activity of the enzyme is associated with the mechanism of prostatic regulation by androgens after castration, which is important in prostate cancer | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
17beta-HSOR | - |
Homo sapiens |
17beta-hydroxysteroid oxidoreductase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens |