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Literature summary for 1.1.1.49 extracted from

  • Maleki, S.; Maerk, M.; Valla, S.; Ertesvag, H.
    Mutational analyses of glucose dehydrogenase and glucose-6-phosphate dehydrogenase genes in Pseudomonas fluorescens reveal their effects on growth and alginate production (2015), Appl. Environ. Microbiol., 81, 3349-3356.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.1.49

Activating Compound

Activating Compound Comment Organism Structure
ATP isoform Zwf-2 is active in the presence of 3m MATP, and then only with NADP+ as a coenzyme Pseudomonas fluorescens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-glucose 6-phosphate + NADP+ Pseudomonas fluorescens
-
 6-phospho-D-glucono-1,5-lactone + NADPH + H+
-
 ir
D-glucose 6-phosphate + NADP+ Pseudomonas fluorescens NCIMB 10525
-
 6-phospho-D-glucono-1,5-lactone + NADPH + H+
-
 ir

Organism

Organism UniProt Comment Textmining
Pseudomonas fluorescens
-
-
-
Pseudomonas fluorescens NCIMB 10525
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-glucose 6-phosphate + NADP+
-
 Pseudomonas fluorescens 6-phospho-D-glucono-1,5-lactone + NADPH + H+
-
 ir
D-glucose 6-phosphate + NADP+
-
 Pseudomonas fluorescens NCIMB 10525 6-phospho-D-glucono-1,5-lactone + NADPH + H+
-
 ir

Synonyms

Synonyms Comment Organism
G6PDH
-
 Pseudomonas fluorescens
glucose-6-phosphate dehydrogenase
-
 Pseudomonas fluorescens
zwf-1 isozyme Pseudomonas fluorescens
Zwf-2 isozyme Pseudomonas fluorescens

Cofactor

Cofactor Comment Organism Structure
NAD+ the enzyme prefers NADP+ as a coenzyme, although NAD+ is also accepted Pseudomonas fluorescens
NADP+ the enzyme prefers NADP+ as a coenzyme, although NAD+ is also accepted Pseudomonas fluorescens

General Information

General Information Comment Organism
malfunction disruption of the gene zwf-1 results in increased alginate production when glycerol is used as the carbon source Pseudomonas fluorescens