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Literature summary for 1.1.1.49 extracted from
- Changes in the glucose-6-phosphate dehydrogenase activity in granulosa cells during follicular atresia in ewes (2009), Reproduction, 137, 979-986.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ovis aries | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | G6PD activity is higher in healthy small rather than large follicles, with similar glutathione concentration in both cases. Activity of G6PD decreases in atretic small follicles, but not in large ones. Specific activity of G6PD and glutathione concentrations in the atretic follicular fluid are lower than those in granulosa cells (10- and 5times respectively) in all kind of follicles. The higher G6PD activity in the small follicles may be related to granulosa cell proliferation, follicular growth, and a lower sensitivity to oxidative stress when compared with large follicles. Lower G6PD activity in large follicles indicating a higher susceptibility to oxidative stress associates to apoptosis progression in follicle atresia | Ovis aries | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| G6PD | - |
Ovis aries |
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Release 2023.1 (January 2023)
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