KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.04 | - |
D-glucose 6-phosphate | 22°C, liver extralesional parenchyma | Rattus norvegicus | |
0.2 | - |
D-glucose 6-phosphate | 22°C, normal liver parenchyma | Rattus norvegicus | |
1.9 | - |
D-glucose 6-phosphate | 22°C, liver (pre)neoplastic lesions | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucose 6-phosphate + NADP+ | Rattus norvegicus | key regulatory enzyme of the pentose phosphate pathway, regulation mechanism study | D-glucono-1,5-lactone 6-phosphate + NADPH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epithelium | of vile ducts and blood vessel walls in portal tracts | Rattus norvegicus | - |
hepatocellular carcinoma cell | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
additional information | distribution pattern | Rattus norvegicus | - |
parenchyma | extralesional and wild-type, the lesions show a 20fold higher, and extralesional parenchyma a 2fold higher, virtual flux at physiological substrate concentrations compared to normal parenchyma | Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
quantification by in situ hydridization and immunohistochemistry | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucose 6-phosphate + NADP+ | - |
Rattus norvegicus | D-glucono-1,5-lactone 6-phosphate + NADPH + H+ | - |
? | |
D-glucose 6-phosphate + NADP+ | key regulatory enzyme of the pentose phosphate pathway, regulation mechanism study | Rattus norvegicus | D-glucono-1,5-lactone 6-phosphate + NADPH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
G6PD | - |
Rattus norvegicus |
glucose-6-phosphate dehydrogenase | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
22 | - |
assay at room temperature | Rattus norvegicus |