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Literature summary for 1.1.1.44 extracted from

  • Price, N.E.; Cook, P.F.
    Kinetic and chemical mechanisms of the sheep liver 6-phosphogluconate dehydrogenase (1996), Arch. Biochem. Biophys., 336, 215-223.
    View publication on PubMed
Search for more literature for 1.1.1.44

Cloned(Commentary)

Cloned (Comment) Organism
amino acid sequence of the sheep liver enzyme deduced from cDNA clones Ovis aries

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4
-
 2-deoxy-6-phosphogluconate
-
 Ovis aries

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
50000
-
 2 * 50000 Ovis aries
52000
-
 2 * 52000 Ovis aries

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6-phospho-D-gluconate + NADP+ Ovis aries
-
 D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r

Organism

Organism UniProt Comment Textmining
Ovis aries
-
 sheep
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Ovis aries
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-deoxy-6-phosphogluconate + NADP+
-
 Ovis aries 2-deoxy-3-oxo 6-phosphogluconate + NADPH
-
 ?
6-O-phosphono-D-mannonic acid + NADP+
-
 Ovis aries ? + NADPH
-
 ?
6-phospho-D-gluconate + NADP+
-
 Ovis aries D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
additional information 6-phosphogalactonate is no substrate Ovis aries ?
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 50000 Ovis aries
dimer 2 * 52000 Ovis aries