Cloned (Comment) | Organism |
---|---|
gene At1g65930 | Arabidopsis thaliana |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-morpholinosydnonimine | 44% inhibition at 5 mM of leaf and root enzymes | Arabidopsis thaliana | |
GSH | inhibits the leaf enzyme by 40% at 5 mM, but not the root enzyme | Arabidopsis thaliana | |
H2O2 | affects the root enzyme slightly but not the enzyme from leaves | Arabidopsis thaliana | |
peroxynitrite | - |
Arabidopsis thaliana | |
S-nitrosoglutathione | 70.5% inhibition at 5 mM of the leaf enzyme, 37.3% of the root enzyme | Arabidopsis thaliana |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0044 | - |
NADP+ | pH 7.6, 25°C, leaf enzyme | Arabidopsis thaliana | |
0.042 | - |
D-isocitrate | pH 7.6, 25°C, leaf enzyme | Arabidopsis thaliana | |
0.0616 | - |
NADP+ | pH 7.6, 25°C, root enzyme | Arabidopsis thaliana | |
0.239 | - |
D-isocitrate | pH 7.6, 25°C, root enzyme | Arabidopsis thaliana |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Arabidopsis thaliana | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-isocitrate + NADP+ | Arabidopsis thaliana | - |
2-oxoglutarate + CO2 + NADPH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | Q9SRZ6 | gene At1g65930 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leaf | - |
Arabidopsis thaliana | - |
root | - |
Arabidopsis thaliana | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-isocitrate + NADP+ | - |
Arabidopsis thaliana | 2-oxoglutarate + CO2 + NADPH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NADP-dependent isocitrate dehydrogenase | - |
Arabidopsis thaliana |
NADP-ICDH | - |
Arabidopsis thaliana |
NADP-isocitrate dehydrogenase | - |
Arabidopsis thaliana |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
45 | - |
root enzyme | Arabidopsis thaliana |
60 | - |
leaf enzyme | Arabidopsis thaliana |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.6 | - |
assay at | Arabidopsis thaliana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Arabidopsis thaliana |