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Literature summary for 1.1.1.41 extracted from

  • Pinheiro de Carvalho, M.A.A.; Popova, T.N.; Dos Santos, T.M.M.; Zherebtsov, N.A.
    Effect of metabolites of gamma-aminobutyric shunt on activities of NAD- and NADP-isocitrate dehydrogenases and aconitate hydratase from higher plants (2003), Biol. Bull., 30, 236-242.
No PubMed abstract available
Search for more literature for 1.1.1.41

Activating Compound

Activating Compound Comment Organism Structure
additional information enzyme is not affected by gamma-aminobutyric acid Zea mays

Inhibitors

Inhibitors Comment Organism Structure
gamma-aminobutyric acid slight inhibition Pisum sativum
glutamate slight inhibition Pisum sativum
additional information enzyme is not affected by gamma-aminobutyric acid and glutamate Zea mays
succinate slight inhibition Pisum sativum
succinate slight inhibition Zea mays
Succinic semialdehyde slight inhibition Pisum sativum
Succinic semialdehyde slight inhibition Zea mays

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion exclusively Pisum sativum 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+
-
 Pisum sativum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
isocitrate + NAD+ Pisum sativum
-
 2-oxoglutarate + CO2 + NADH + H+
-
 ?
isocitrate + NAD+ Zea mays
-
 2-oxoglutarate + CO2 + NADH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Pisum sativum
-
-
-
Zea mays
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Pisum sativum
-
scutellum
-
 Zea mays
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.7
-
-
 Pisum sativum
2.9
-
-
 Zea mays

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
isocitrate + NAD+
-
 Pisum sativum 2-oxoglutarate + CO2 + NADH + H+
-
 ?
isocitrate + NAD+
-
 Zea mays 2-oxoglutarate + CO2 + NADH + H+
-
 ?

Synonyms

Synonyms Comment Organism
NAD-ICDH
-
 Pisum sativum
NAD-ICDH
-
 Zea mays
NAD-isocitrate dehydrogenase
-
 Pisum sativum
NAD-isocitrate dehydrogenase
-
 Zea mays

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Pisum sativum
25
-
 assay at Zea mays

Cofactor

Cofactor Comment Organism Structure
NAD+ specific for Pisum sativum
NAD+ specific for Zea mays