Literature summary for 1.1.1.407 extracted from

Wichelecki, D.; Vetting, M.; Chou, L.; Al-Obaidi, N.; Bouvier, J.; Almo, S.; Gerlt, J.
ATP-binding cassette (ABC) transport system solute-binding protein-guided identification of novel D-altritol and galactitol catabolic pathways in Agrobacterium tumefaciens C58 (2015), J. Biol. Chem., 290, 28963-28976.

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KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.4	-	D-altritol	pH 9.0, 25°C	Agrobacterium fabrum

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	enzyme is a zinc-binding dehydrogenase, member of Pfam Family PF00107	Agrobacterium fabrum

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
D-altritol + NAD+	Agrobacterium fabrum	-	D-tagatose + NADH + H+	-	?
D-altritol + NAD+	Agrobacterium fabrum C58	-	D-tagatose + NADH + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Agrobacterium fabrum	A9CES3	-	-
Agrobacterium fabrum C58	A9CES3	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-altritol + NAD+	-	Agrobacterium fabrum	D-tagatose + NADH + H+	-	?
D-altritol + NAD+	-	Agrobacterium fabrum C58	D-tagatose + NADH + H+	-	?
D-arabitol + NAD+	-	Agrobacterium fabrum	? + NADH + H+	-	?
D-arabitol + NAD+	-	Agrobacterium fabrum C58	? + NADH + H+	-	?
D-mannitol + NAD+	-	Agrobacterium fabrum	? + NADH + H+	-	?
D-mannitol + NAD+	-	Agrobacterium fabrum C58	? + NADH + H+	-	?
additional information	D-altritol is oxidized at a significantly greater rate than D-mannitol and D-arabitol	Agrobacterium fabrum	?	-	?
additional information	D-altritol is oxidized at a significantly greater rate than D-mannitol and D-arabitol	Agrobacterium fabrum C58	?	-	?

Synonyms

Synonyms	Comment	Organism
Atu3163	-	Agrobacterium fabrum

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
1.9	-	D-altritol	pH 9.0, 25°C	Agrobacterium fabrum

kcat/KM [mM/s]

kcat/KM Value [1/mMs^-1]	kcat/KM Value Maximum [1/mMs^-1]	Substrate	Comment	Organism	Structure
1.4	-	D-altritol	pH 9.0, 25°C	Agrobacterium fabrum

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Release 2023.1 (January 2023)