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Literature summary for 1.1.1.40 extracted from

  • Singh, R.; Dangol, S.; Chen, Y.; Choi, J.; Cho, Y.S.; Lee, J.E.; Choi, M.O.; Jwa, N.S.
    Magnaporthe oryzae effector AVR-Pii helps to establish compatibility by inhibition of the rice NADP-malic enzyme resulting in disruption of oxidative burst and host innate immunity (2016), Mol. Cells, 39, 426-438.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Rosetta cells Oryza sativa

Inhibitors

Inhibitors Comment Organism Structure
Magnaporthe oryzae effector AVR-Pii
-
 Oryza sativa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-malate + NADP+ Oryza sativa
-
 pyruvate + CO2 + NADPH
-
 ?

Organism

Organism UniProt Comment Textmining
Oryza sativa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
nickel affinity column chromatography Oryza sativa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-malate + NADP+
-
 Oryza sativa pyruvate + CO2 + NADPH
-
 ?

Synonyms

Synonyms Comment Organism
ADP-malic enzyme2
-
 Oryza sativa
NADP-ME2
-
 Oryza sativa

Cofactor

Cofactor Comment Organism Structure
NADP+
-
 Oryza sativa

General Information

General Information Comment Organism
malfunction deletion of the enzyme gene in a Magnaporthe oryzae-resistant rice cultivar disrupts innate immunity against the rice blast fungus Oryza sativa