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Literature summary for 1.1.1.40 extracted from

  • Pengelly, J.; Tan, J.; Furbank, R.; von Caemmerer, S.
    Antisense reduction of NADP-malic enzyme in Flaveria bidentis reduces flow of CO2 through the C4 cycle (2012), Plant Physiol., 160, 1070-1080.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.1.40

Protein Variants

Protein Variants Comment Organism
additional information generation of an antisense construct targeting the C4 isoform of NADP-malic enzyme, transformation of Flaveria bidentis via Agrobacterium tumefaciens, transgenic Flaveria bidentis plants exhibit a 34% to 75% reduction in NADP-ME activity relative to the wild-type with no visible growth phenotype. In transgenic plants, CO2 assimilation rates at high intercellular CO2 are significantly reduced, whereas the in vitro activities of both phosphoenolpyruvate carboxylase and Rubisco are increased Flaveria bidentis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-malate + NADP+ Flaveria bidentis
-
 pyruvate + CO2 + NADPH
-
 ?

Organism

Organism UniProt Comment Textmining
Flaveria bidentis
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bundle sheath cell
-
 Flaveria bidentis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-malate + NADP+
-
 Flaveria bidentis pyruvate + CO2 + NADPH
-
 ?

Synonyms

Synonyms Comment Organism
NADP-malic enzyme
-
 Flaveria bidentis
NADP-ME
-
 Flaveria bidentis

Cofactor

Cofactor Comment Organism Structure
NADP+
-
 Flaveria bidentis

General Information

General Information Comment Organism
malfunction antisense reduction of NADP-ME alters C3-C4 cycle coordination. Increase in Rubisco and phosphoenolpyruvate carboxylase activity and leaf nitrogen in low-NADP-ME antisense plants Flaveria bidentis
physiological function NADP-malic enzyme is the primary enzyme decarboxylating malate in bundle sheath cells to supply CO2 to Rubisco Flaveria bidentis