Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2R)-[(bromoacetyl)oxy]mandelic acid | 8 mM, greater than 95% inactivation after 2 h at 27°C. Inactivation is a pseudo-first-order process. D-Mandelate protects against inactivation. The inhibitor is covalently bound | Rhodotorula graminis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-mandelate + NAD+ | Rhodotorula graminis | first enzyme of the mandelate pathway in the yeast Rhodotorula graminis | phenylglyoxylate + NADH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rhodotorula graminis | Q7LLW9 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-mandelate + NAD+ | first enzyme of the mandelate pathway in the yeast Rhodotorula graminis | Rhodotorula graminis | phenylglyoxylate + NADH + H+ | - |
? | |
(R)-mandelate + NAD+ | the enzyme transfers the pro-R hydrogen atom from NADH during the reduction of phenylglyoxylate | Rhodotorula graminis | phenylglyoxylate + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
D(-)-mandelate dehydrogenase | - |
Rhodotorula graminis |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.9 | - |
assay at | Rhodotorula graminis |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
2.4 | - |
(2R)-[(bromoacetyl)oxy]mandelic acid | pH 5.9, temperature not specified in the publication | Rhodotorula graminis |