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Literature summary for 1.1.1.37 extracted from

  • Hadzi-Taskovic Sukalovic, V.; Vuletic, M.; Markovic, K.; Vucinic, Z.
    Cell wall-associated malate dehydrogenase activity from maize roots (2011), Plant Sci., 181, 465-470.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
(S)-malate 24.2% substrate inhibition at 20 mM Zea mays
4-coumaric acid 13.4% inhibition at 0.1 mM Zea mays
ATP 43.7% inhibition at 5 mM Zea mays
Cu2+ 25% inhibition at 0.1 mM Zea mays
ferulic acid 24.5% inhibition at 0.1 mM Zea mays
oxaloacetate 27.4% substrate inhibition at 1 mM Zea mays
Zn2+ 25% inhibition at 1 mM Zea mays

Localization

Localization Comment Organism GeneOntology No. Textmining
cell wall bound Zea mays 5618
-

Metals/Ions

Metals/Ions Comment Organism Structure
phosphate 6.6% activation at 50 mM compared to Tris at 50 mM Zea mays

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-malate + NAD+ Zea mays
-
oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+ Zea mays VA35
-
oxaloacetate + NADH + H+
-
r

Organism

Organism UniProt Comment Textmining
Zea mays
-
-
-
Zea mays VA35
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
root much greater activity of cell wall-associated malate dehydrogenase in the intensively growing lateral roots compared to primary root with decreased growth rates Zea mays
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-malate + NAD+
-
Zea mays oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+
-
Zea mays VA35 oxaloacetate + NADH + H+
-
r

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
assay at Zea mays

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
oxaloacetate reduction Zea mays
8.5
-
L-malate oxidation Zea mays

pH Range

pH Minimum pH Maximum Comment Organism
5.5 8 oxaloacetate reduction, 50% of maximal activity at pH 5.5, maximal activity at pH 7.5 Zea mays
6 9 malate oxidation, 10% of maximal activity at pH 6.0, maximal activity at pH 8.5 Zea mays

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Zea mays
NADH
-
Zea mays

General Information

General Information Comment Organism
malfunction exposure of maize plants to excess concentrations of Zn2+ and Cu2+ in the hydroponic solution inhibited lateral root growth, decreased malate dehydrogenase activity and changed isoform profiles Zea mays
additional information a significant decrease of both mass and elongation of maize roots and shoots, as well as loss of root turgor and completely repressed lateral root growth were demonstrated in 0.1 mM Cu2+ and 5 mM Zn2+ treatments, overview Zea mays