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Literature summary for 1.1.1.37 extracted from

  • Lagana, G.; Giacobbe, S.; Bellocco, E.; Mannucci, C.; Galtieri, A.; Ficarra, S.; Kotyk, A.; Leuzzi, U.
    Lactate and malate dehydrogenase in the fan-shell associated shrimp, Pontonia pinnophylax (Otto): effects of temperature and urea (2007), J. Exp. Mar. Biol. Ecol., 349, 27-34.
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Search for more literature for 1.1.1.37

Inhibitors

Inhibitors Comment Organism Structure
Urea enzyme activity and electrophoretic pattern of MDH and lactate dehydrogenase, EC 1.1.1.27, compared in relation to heat and urea inactivation, LDH is more sensitive than MDH, overview Pontonia pinnophylax

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol cytosolic isozyme Pontonia pinnophylax 5829
-
mitochondrion mitochondrial isozyme Pontonia pinnophylax 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-malate + NAD+ Pontonia pinnophylax
-
 oxaloacetate + NADH + H+
-
 r

Organism

Organism UniProt Comment Textmining
Pontonia pinnophylax
-
 inhabiting the mantle cavity of host Pinna nobilis
-

Purification (Commentary)

Purification (Comment) Organism
native enzyme partially by subcellular fractionation Pontonia pinnophylax

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 enzyme activity and electrophoretic pattern of MDH and lactate dehydrogenase, EC 1.1.1.27, compared in relation to heat and urea inactivation, overview Pontonia pinnophylax

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-malate + NAD+
-
 Pontonia pinnophylax oxaloacetate + NADH + H+
-
 r
(S)-malate + NAD+ enzyme activity and electrophoretic pattern of MDH and lactate dehydrogenase, EC 1.1.1.27, compared in relation to heat and urea inactivation, overview Pontonia pinnophylax oxaloacetate + NADH + H+
-
 r

Subunits

Subunits Comment Organism
More enzyme activity and electrophoretic pattern of MDH and lactate dehydrogenase, EC 1.1.1.27, compared in relation to heat and urea inactivation, overview Pontonia pinnophylax

Synonyms

Synonyms Comment Organism
malate dehydrogenase
-
 Pontonia pinnophylax
MDH
-
 Pontonia pinnophylax

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at, oxaloacetate reduction Pontonia pinnophylax

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
65
-
 enzyme activity and electrophoretic pattern of MDH and lactate dehydrogenase, LDH EC 1.1.1.27, compared in relation to heat and urea inactivation, MDH is more sensitive than LDH, overview Pontonia pinnophylax

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at, oxaloacetate reduction Pontonia pinnophylax

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Pontonia pinnophylax
NADH
-
 Pontonia pinnophylax