Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | not inhibited by p-hydroxymercuribenzoate or N-ethylmaleimide from 0.1-10 mM | Pigeon |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.74 | - |
acetoacetyl-CoA | - |
Pigeon |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pigeon | - |
- |
- |
Purification (Comment) | Organism |
---|---|
fractionated with ammonium sulfate | Pigeon |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Pigeon | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
87.9 | - |
fed pigeons livers | Pigeon |
170.1 | - |
fasted pigeons livers | Pigeon |
250 | - |
- |
Pigeon |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetoacetyl-CoA + NADPH + H+ | - |
Pigeon | D-beta-hydroxybutyryl-CoA + NADP+ | - |
ir | |
acetoacetyl-CoA + NADPH + H+ | - |
Pigeon | (3R)-3-hydroxybutyryl-CoA + NADP+ | - |
r | |
additional information | not: crotonyl-CoA | Pigeon | ? | - |
? | |
additional information | not: octanoyl-CoA | Pigeon | ? | - |
? | |
additional information | not: beta-hydroxybutyryl-CoA | Pigeon | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Pigeon |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.5 | 8.5 | 70-35% of initial acetoacetyl-CoA reduced | Pigeon |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
above pH 8.5 acetoacetyl-CoA not stable | Pigeon |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Pigeon | |
NADPH | - |
Pigeon |