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Literature summary for 1.1.1.35 extracted from

  • Teufel, R.; Mascaraque, V.; Ismail, W.; Voss, M.; Perera, J.; Eisenreich, W.; Haehnel, W.; Fuchs, G.
    Bacterial phenylalanine and phenylacetate catabolic pathway revealed (2010), Proc. Natl. Acad. Sci. USA, 107, 14390-14395.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.1.35

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(3S)-3-hydroxyadipyl-CoA + NAD+ Escherichia coli
-
 3-oxoadipyl-CoA + NADH + H+
-
 ?
(3S)-3-hydroxyadipyl-CoA + NAD+ Pseudomonas sp.
-
 3-oxoadipyl-CoA + NADH + H+
-
 ?
(3S)-3-hydroxyadipyl-CoA + NAD+ Pseudomonas sp. Y2
-
 3-oxoadipyl-CoA + NADH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Pseudomonas sp.
-
-
-
Pseudomonas sp. Y2
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(3S)-3-hydroxyadipyl-CoA + NAD+
-
 Escherichia coli 3-oxoadipyl-CoA + NADH + H+
-
 ?
(3S)-3-hydroxyadipyl-CoA + NAD+
-
 Pseudomonas sp. 3-oxoadipyl-CoA + NADH + H+
-
 ?
(3S)-3-hydroxyadipyl-CoA + NAD+
-
 Pseudomonas sp. Y2 3-oxoadipyl-CoA + NADH + H+
-
 ?

Synonyms

Synonyms Comment Organism
3-hydroxyadipyl-CoA dehydrogenase
-
 Escherichia coli
3-hydroxyadipyl-CoA dehydrogenase
-
 Pseudomonas sp.
3-hydroxyadipyl-CoA dehydrogenase (NAD+) (probably (S)-3-specific)
-
 Escherichia coli
3-hydroxyadipyl-CoA dehydrogenase (NAD+) (probably (S)-3-specific)
-
 Pseudomonas sp.
More PaaH is a member of the alcohol dehydrogenase family Escherichia coli
More PaaH is a member of the alcohol dehydrogenase family Pseudomonas sp.
PaaH
-
 Escherichia coli
PaaH
-
 Pseudomonas sp.

Cofactor

Cofactor Comment Organism Structure
NAD+ specific for Escherichia coli
NAD+ specific for Pseudomonas sp.

General Information

General Information Comment Organism
physiological function PaaH functions as an NAD+-dependent [probably (S)-3–specific] 3-hydroxyadipyl-CoA dehydrogenase forming 3-oxoadipyl-CoA in the aerobic phenylacetate pathway, overview Escherichia coli
physiological function PaaH functions as an NAD+-dependent [probably (S)-3–specific] 3-hydroxyadipyl-CoA dehydrogenase forming 3-oxoadipyl-CoA in the aerobic phenylacetate pathway, overview Pseudomonas sp.