Protein Variants | Comment | Organism |
---|---|---|
K171A | mutation in conserved catalytic triad, complete loss of activity | Podophyllum peltatum |
S153A | mutation in conserved catalytic triad, severe reduction of activity | Podophyllum peltatum |
Y167A | mutation in conserved catalytic triad, complete loss of activity | Podophyllum peltatum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Podophyllum peltatum | Q94KL8 | - |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
3500 | - |
wild-type, pH 8.8, 22°C | Podophyllum peltatum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(-)-secoisolariciresinol + 2 NAD+ | NAD+ binds first followed by the substrate (-)-secoisolariciresinol. For hydride transfer, the incoming hydride abstracted from the substrate takes up the pro-S position in the NADH formed | Podophyllum peltatum | (-)-matairesinol + 2 NADH + 2 H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SDH | - |
Podophyllum peltatum |