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Literature summary for 1.1.1.320 extracted from

  • Maruyama, R.; Nishizawa, M.; Itoi, Y.; Ito, S.; Inoue, M.
    Isolation and expression of a Bacillus cereus gene encoding benzil reductase (2001), Biotechnol. Bioeng., 75, 630-633.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene yueD, Bacillus cereus library screening in Escherichia coli and cloning of the gene encoding the benzil reductase, DNA and amino acid sequence determination and analysis, sequence comparisons, expression in Escherichia coli strain DH5alpha Bacillus cereus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-benzoin + NADP+ Bacillus cereus stereospecific asymmetric reduction of benzil to (S)-benzoin benzil + NADPH + H+
-
r
(S)-benzoin + NADP+ Bacillus cereus Tim-r01 stereospecific asymmetric reduction of benzil to (S)-benzoin benzil + NADPH + H+
-
r

Organism

Organism UniProt Comment Textmining
Bacillus cereus Q8RJB2
-
-
Bacillus cereus Tim-r01 Q8RJB2
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-benzoin + NADP+ stereospecific asymmetric reduction of benzil to (S)-benzoin Bacillus cereus benzil + NADPH + H+
-
r
(S)-benzoin + NADP+ stereospecific asymmetric reduction of benzil to (S)-benzoin Bacillus cereus Tim-r01 benzil + NADPH + H+
-
r

Cofactor

Cofactor Comment Organism Structure
NADP+
-
Bacillus cereus
NADPH
-
Bacillus cereus

General Information

General Information Comment Organism
evolution the enzyme is a member of the short-chain dehydrogenase/reductase, SDR, family Bacillus cereus