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Literature summary for 1.1.1.312 extracted from
- Isolation and identification of the reaction product of alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase (1979), J. Biochem., 86, 1671-1677.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Pseudomonas straminea | 2-pyrone-4,6-dicarboxylic acid may be a metabolic intermediate in the bacterial metabolism of protocatechuic acid | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas straminea | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde + NADP+ | - |
Pseudomonas straminea | 4-carboxy-2-hydroxy-cis,cis-muconate + NADPH | following intramolecular dehydrogenation to the lactone 2-pyrone-4,6-dicarboxylic acid | ? | |
| 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde + NADP+ | - |
Pseudomonas straminea | 4-carboxy-2-hydroxy-cis,cis-muconate + NADPH | it is not clear whether the lactonization occurs enzymatically or nonenzymatically | ? | |
| additional information | 2-pyrone-4,6-dicarboxylic acid may be a metabolic intermediate in the bacterial metabolism of protocatechuic acid | Pseudomonas straminea | ? | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADP+ | - |
Pseudomonas straminea | |
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