Activating Compound | Comment | Organism | Structure |
---|---|---|---|
phosphatidylcholine | - |
Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-hydroxybutyrate | substrate inhibition at concentrations above 20 mM, 50% inhibition at 200 mM, cyanylated enzyme is 3fold more active at high substrate concentration | Bos taurus | |
4-mercapto-3-nitrobenzoate | derivatization of enzyme sulfhydryl groups, less than 1% residual activity | Bos taurus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.091 | - |
NADH | - |
Bos taurus | |
0.164 | - |
NADH | cyanylated enzyme | Bos taurus | |
0.55 | - |
NAD+ | - |
Bos taurus | |
0.59 | - |
acetoacetate | - |
Bos taurus | |
0.902 | - |
NAD+ | cyanylated enzyme | Bos taurus | |
2.3 | - |
(R)-3-hydroxybutanoate | - |
Bos taurus | |
8.7 | - |
acetoacetate | cyanylated enzyme | Bos taurus | |
21 | - |
(R)-3-hydroxybutanoate | cyanylated enzyme | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Bos taurus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-3-hydroxybutanoate + NAD+ | Bos taurus | - |
acetoacetate + NADH | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-3-hydroxybutanoate + NAD+ | - |
Bos taurus | acetoacetate + NADH | - |
r | |
(R)-3-hydroxybutanoate + NAD+ | - |
Bos taurus | acetoacetate + NADH + H+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Bos taurus |