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Literature summary for 1.1.1.3 extracted from

  • Jacques, S.L.; Ejim, L.J.; Wright, G.D.
    Homoserine dehydrogenase from Saccharomyces cerevisiae: kinetic mechanism and stereochemistry of hydride transfer (2001), Biochim. Biophys. Acta, 1544, 42-54.
    View publication on PubMed
Search for more literature for 1.1.1.3

Inhibitors

Inhibitors Comment Organism Structure
(S)-2-amino-4-oxo-5-hydroxypentanoic acid RI-331 Saccharomyces cerevisiae
H-(1,2,4-triazol-3-yl)-DL-alanine
-
 Saccharomyces cerevisiae
L-threonine weakly inhibits reverse but not forward reaction Saccharomyces cerevisiae
methionine weakly inhibits reverse but not forward reaction Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-aspartate 4-semialdehyde + NAD(P)H Saccharomyces cerevisiae kinetic mechanism L-homoserine + NAD(P)+
-
 r

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-aspartate 4-semialdehyde + NAD(P)H
-
 Saccharomyces cerevisiae L-homoserine + NAD(P)+
-
 r
L-aspartate 4-semialdehyde + NAD(P)H kinetic mechanism Saccharomyces cerevisiae L-homoserine + NAD(P)+
-
 r
L-homoserine + NAD(P)+
-
 Saccharomyces cerevisiae L-aspartate 4-semialdehyde + NAD(P)H
-
 r