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Literature summary for 1.1.1.28 extracted from

  • Storey, K.B.
    Lactate dehydrogenase in tissue extracts of the land snail, Helix aspersa: unique adaptation of LDH subunits in a facultative anaerobe (1977), Comp. Biochem. Physiol. B, 56, 181-187.
    View publication on PubMed
Search for more literature for 1.1.1.28

Inhibitors

Inhibitors Comment Organism Structure
pyruvate
-
 Cornu aspersum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.015
-
 NADH
-
 Cornu aspersum
0.02
-
 NAD+
-
 Cornu aspersum
0.42
-
 pyruvate
-
 Cornu aspersum
3.2
-
 (R)-lactate
-
 Cornu aspersum

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
34000
-
 4 * 34000, SDS-PAGE Cornu aspersum
140000
-
 gel filtration Cornu aspersum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(R)-lactate + NAD+ Cornu aspersum
-
 pyruvate + NADH
-
 r

Organism

Organism UniProt Comment Textmining
Cornu aspersum
-
 land snail
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Cornu aspersum
-
foot
-
 Cornu aspersum
-
heart
-
 Cornu aspersum
-
hepatopancreas
-
 Cornu aspersum
-
kidney
-
 Cornu aspersum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R)-lactate + NAD+
-
 Cornu aspersum pyruvate + NADH
-
 r

Subunits

Subunits Comment Organism
tetramer 4 * 34000, SDS-PAGE Cornu aspersum

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.4
-
 reduction of pyruvate Cornu aspersum
9
-
 oxidation of (R)-lactate Cornu aspersum

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Cornu aspersum
NADH
-
 Cornu aspersum