Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | tightly bound, divalent metal ion-dependent enzyme, Zn2+ can be replaced by e.g. Mg2+ | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-(phosphonooxy)threonine + NAD(P)+ | Escherichia coli | involved in the biosynthesis of vitamin B6 | 3-amino-1-hydroxyacetone 1-phosphate + CO2 + NAD(P)H | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
4-phosphooxy-L-threonine + NAD+ = 3-amino-2-oxopropyl phosphate + CO2 + NADH + H+ | 3-amino-1-hydroxyacetone 1-phosphate,i.e. AHAB, is the primary product of the reaction, no formation of 2-amino-3-oxo-4-phosphonooxybutyrate as intermediate is detected, identification by electrospray ionization mass spectrometry | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-(phosphonooxy)threonine + NAD(P)+ | involved in the biosynthesis of vitamin B6 | Escherichia coli | 3-amino-1-hydroxyacetone 1-phosphate + CO2 + NAD(P)H | - |
? | |
4-(phosphonooxy)threonine + NAD(P)+ | i.e. 4-hydroxy-L-threonine-4-phosphate, HTP | Escherichia coli | 3-amino-1-hydroxyacetone 1-phosphate + CO2 + NAD(P)H | i.e. AHAB, primary product of the reaction, no formation of 2-amino-3-oxo-4-phosphonooxybutyrate as intermediate is detected, identification by electrospray ionization mass spectrometry | ? |
Synonyms | Comment | Organism |
---|---|---|
PdxA | - |
Escherichia coli |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Escherichia coli |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD(P)+ | dependent on | Escherichia coli |