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Literature summary for 1.1.1.252 extracted from

  • Conradt, D.; Schätzle, M.; Husain, S.; Müller, M.
    Diversity in reduction with short-chain dehydrogenases: tetrahydroxynaphthalene reductase, trihydroxynaphthalene reductase, and glucose dehydrogenase (2015), ChemCatChem, 7, 3116-3120.
No PubMed abstract available

Organism

Organism UniProt Comment Textmining
Pyricularia oryzae
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,3-dihydronaphthalene-1,4-dione + NADPH + H+
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Pyricularia oryzae (4S)-4-hydroxy-3,4-dihydronaphthalen-1(2H)-one + NADP+ 21% yield, 98% enantiomeric excess ?
3,4-dihydronaphthalen-2(1H)-one + NADPH + H+
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Pyricularia oryzae (2S)-1,2,3,4-tetrahydronaphthalen-2-ol + NADP+ 77% yield, 61% enantiomeric excess ?
5-hydroxy-2,3-dihydronaphthalene-1,4-dione + NADPH + H+
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Pyricularia oryzae (4S)-4,8-dihydroxy-3,4-dihydronaphthalen-1(2H)-one + NADP+ 9% yield, 95% enantiomeric excess ?
6-methoxy-3,4-dihydronaphthalen-2(1H)-one + NADPH + H+
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Pyricularia oryzae (2S)-6-methoxy-1,2,3,4-tetrahydronaphthalen-2-ol + NADP+ 71% yield, 99% enantiomeric excess ?
8-methoxy-3,4-dihydronaphthalen-2(1H)-one + NADPH + H+
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Pyricularia oryzae (2R)-8-methoxy-1,2,3,4-tetrahydronaphthalen-2-ol + NADP+ 75% yield, 99% enantiomeric excess ?