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Literature summary for 1.1.1.251 extracted from

  • Benavente, R.; Esteban-Torres, M.; Kohring, G.W.; Cortes-Cabrera, A.; Sanchez-Murcia, P.A.; Gago, F.; Acebron, I.; de las Rivas, B.; Munoz, R.; Mancheno, J.M.
    Enantioselective oxidation of galactitol 1-phosphate by galactitol-1-phosphate 5-dehydrogenase from Escherichia coli (2015), Acta Crystallogr. Sect. D, 71, 1540-1554.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
structures of open state with Zn2+ in the catalytic site and of the closed state in complex with the polyols Tris and glycerol, respectively. The closed state reveals no bound cofactor. The glycerol binding mode reveals a pentacoordinated zinc ion in complex with a polyol and also a strong hydrogen bond between the primary hydroxyl group and the conserved Glu144 Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ structure shows a pentacoordinated zinc ion in complex with a polyol Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P0A9S3
-
-

Synonyms

Synonyms Comment Organism
GatD
-
Escherichia coli
GPDH
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Escherichia coli

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Escherichia coli