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Literature summary for 1.1.1.25 extracted from
- Partial purification and some properties of shikimate dehydrogenase from tomatoes (1984), Phytochemistry, 23, 497-499.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Borate | - |
Solanum lycopersicum |  |
| Cu2+ | - |
Solanum lycopersicum | |
| Hg2+ | - |
Solanum lycopersicum | |
| N-ethylmaleimide | - |
Solanum lycopersicum | |
| NH4+ | - |
Solanum lycopersicum | |
| p-chloromercuribenzoate | - |
Solanum lycopersicum | |
| protocatechuic acid | - |
Solanum lycopersicum | |
| Zn2+ | - |
Solanum lycopersicum | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.01 | - |
NADP+ | - |
Solanum lycopersicum | |
| 0.038 | - |
shikimate | - |
Solanum lycopersicum | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no requirement for divalent ions | Solanum lycopersicum |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 73000 | - |
gel filtration | Solanum lycopersicum |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| shikimate + NADP+ | Solanum lycopersicum | - |
3-dehydroshikimate + NADPH + H+ | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Solanum lycopersicum | - |
tomato | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| fruit | - |
Solanum lycopersicum | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.28 | - |
- |
Solanum lycopersicum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| shikimate + NADP+ | - |
Solanum lycopersicum | 3-dehydroshikimate + NADPH + H+ | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | - |
5 min, 85% loss of activity | Solanum lycopersicum |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9.1 | - |
- |
Solanum lycopersicum |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6 | 11 | no activity below and above | Solanum lycopersicum |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no activity with NAD+ | Solanum lycopersicum | |
| NADP+ | specific for | Solanum lycopersicum | |
| NADPH | specific for | Solanum lycopersicum | |
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