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Literature summary for 1.1.1.236 extracted from

  • Dehghan, E.; Shahriari Ahmadi, F.; Ghotbi Ravandi, E.; Reed, D.W.; Covello, P.S.; Bahrami, A.R.
    An atypical pattern of accumulation of scopolamine and other tropane alkaloids and expression of alkaloid pathway genes in Hyoscyamus senecionis (2013), Plant Physiol. Biochem., 70C, 188-194.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
tropinone + NADPH + H+ Hyoscyamus muticus tropinone reductase I tropine + NADP+
-
?
tropinone + NADPH + H+ Hyoscyamus senecionis tropinone reductase I tropine + NADP+
-
?

Organism

Organism UniProt Comment Textmining
Hyoscyamus muticus
-
-
-
Hyoscyamus senecionis
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf hyoscyamine is the main tropane alkaloid of the leaf and root of Hyoscyamus muticus Hyoscyamus muticus
-
leaf scopolamine is the main tropane alkaloid compound in Hyoscyamus senecionis leaves Hyoscyamus senecionis
-
root hyoscyamine is the main tropane alkaloid of the leaf and root of Hyoscyamus muticus Hyoscyamus muticus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
tropinone + NADPH + H+ tropinone reductase I Hyoscyamus muticus tropine + NADP+
-
?
tropinone + NADPH + H+ tropinone reductase I Hyoscyamus senecionis tropine + NADP+
-
?

Synonyms

Synonyms Comment Organism
tropinone reductase I
-
Hyoscyamus muticus
tropinone reductase I
-
Hyoscyamus senecionis

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Hyoscyamus muticus
NADPH
-
Hyoscyamus senecionis

General Information

General Information Comment Organism
metabolism tropinone reductase I is involved in the scopolamine biosynthetic pathway, overview. Hyoscyamine is the main tropane alkaloid of the leaf and root of Hyoscyamus muticus. Higher amounts of littorine as an intermediate compound in the pathway, and 3'-hydroxylittorine are accumulated in roots than in other organs Hyoscyamus muticus
metabolism tropinone reductase I is involved in the scopolamine biosynthetic pathway, overview. Scopolamine is the main tropane alkaloid compound in Hyoscyamus senecionis leaves. Higher amounts of littorine as an intermediate compound in the pathway, and 3'-hydroxylittorine are accumulated in roots than in other organs Hyoscyamus senecionis