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Literature summary for 1.1.1.219 extracted from

  • Kumar, V.; Nadda, G.; Kumar, S.; Yadav, S.
    Transgenic Tobacco overexpressing tea cDNA encoding dihydroflavonol 4-reductase and anthocyanidin reductase induces early flowering and provides biotic stress tolerance (2013), PLoS ONE, 8, e65535.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene CsDFR, recombinant overexpression in Nicotiana tabacum cv. Xanthi leaves Camellia sinensis

Protein Variants

Protein Variants Comment Organism
additional information transgenic tobacco overexpressing tea cDNA encoding dihydroflavonol 4-reductase and anthocyanidin reductase induces early flowering, and better seed yield, and provides biotic stress tolerance Camellia sinensis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dihydrokaempferol + NADPH + H+ Camellia sinensis
-
leucopelargonidin + NADP+
-
?
dihydromyricetin + NADPH + H+ Camellia sinensis
-
leucodelphinidin + NADP+
-
?

Organism

Organism UniProt Comment Textmining
Camellia sinensis Q6DT40 cv. UPASI-10
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dihydrokaempferol + NADPH + H+
-
Camellia sinensis leucopelargonidin + NADP+
-
?
dihydromyricetin + NADPH + H+
-
Camellia sinensis leucodelphinidin + NADP+
-
?

Synonyms

Synonyms Comment Organism
CsDFR
-
Camellia sinensis
DFR
-
Camellia sinensis
flavan-3-ol NADPH-dihydromycertin reductase
-
Camellia sinensis

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Camellia sinensis

General Information

General Information Comment Organism
physiological function transgenic tobacco overexpressing tea cDNA encoding dihydroflavonol 4-reductase and anthocyanidin reductase induces early flowering, and provides biotic stress tolerance, better seed yield, and higher content of flavonoids, e.g. of flavan-3-ols such as catechin, epicatechin and epicatechingallate. The recombinant plants show free increased radical scavenging activity and better resistance to oxidative stress or against infestation by a tobacco leaf cutworm Spodoptera litura Camellia sinensis