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Literature summary for 1.1.1.210 extracted from
- Identification of histidine residue in the active site of fetal lamb 3beta,20alpha-hydroxysteroid oxidoreductase (1991), Sheng Wu Hua Xue Yu Sheng Wu Wu Li Jin Zhan, 18, 113-117.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5alpha-dihydrotestosterone 17-bromoacetate | competitive inhibition of 3beta- and 20alpha-reductase activity, time dependent and simultaneous, complete inactivation | Ovis aries |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| soluble | - |
Ovis aries | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ovis aries | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| 5alpha-androstan-3beta,17beta-diol + NADP+ = 17beta-hydroxy-5alpha-androstan-3-one + NADPH + H+ | 3beta and 20alpha substrates share the same active site | Ovis aries |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | fetal | Ovis aries | - |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADP+ | - |
Ovis aries | |
| NADPH | - |
Ovis aries | |
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