Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2-benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-8-yl)-acetic acid | an aldose reductase inhibitor and antioxidant of zwitterionic nature | Rattus norvegicus | |
stobadine | i.e. (-)-cis-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3,-b]indole | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Rattus norvegicus Wistar | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
aldose reductase | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0182 | - |
pH and temperature not specified in the publication | Rattus norvegicus | (2-benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-8-yl)-acetic acid |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is involved in sorbitol accumulation in red blood cells after peroxide, e.g. 2,2'-azobis(2-amidinopropane) hydrochloride and tert-butyl hydroperoxide, induced hemolysis, overview | Rattus norvegicus |