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Literature summary for 1.1.1.205 extracted from

  • Hansen, B.; Genee, H.; Kaas, C.; Nielsen, J.; Regueira, T.; Mortensen, U.; Frisvad, J.; Patil, K.
    A new class of IMP dehydrogenase with a role in self-resistance of mycophenolic acid producing fungi (2011), BMC Microbiol., 11, 202.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Penicillium brevicompactum F1DBB2
-
-

Synonyms

Synonyms Comment Organism
IMPDH-B
-
 Penicillium brevicompactum
mpaF
-
 Penicillium brevicompactum

General Information

General Information Comment Organism
physiological function heterologous expression of IMP dehydrogenase gene mpaF dramatically increases mycophenolic acid resistance in Aspergillus nidulans, which does not produce mycophenolic acid.The growth of an Aspergillus nidulans strain expressing mpaF is only marginally affected by mycophenolic acid at concentrations as high as 200 microg/ml Penicillium brevicompactum