Literature summary for 1.1.1.205 extracted from

Gunter, J.H.; Thomas, E.C.; Lengefeld, N.; Kruger, S.J.; Worton, L.; Gardiner, E.M.; Jones, A.; Barnett, N.L.; Whitehead, J.P.
Characterisation of inosine monophosphate dehydrogenase expression during retinal development: Differences between variants and isoforms (2008), Int. J. Biochem. Cell Biol., 40, 1716-1728.

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Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	Q6P9U9	IMPDH2	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
retina	inosine monophosphate dehydrogenase is present in all immature cells throughout the retina during embryonic and neonatal development. Following eye opening and cell differentiation, its distribution is restricted to the photoreceptors and bipolar cell, becoming prominent in Muller cells with ageing. Type I enzyme does not play a role in early retinal development but type Igamma has greater activity after postnatal day 10. All forms of type I show an increased propensity to form intracellular macrostructures compared to type II	Rattus norvegicus	-

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Release 2023.1 (January 2023)