Cloned (Comment) | Organism |
---|---|
- |
Borreliella burgdorferi |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
GMP | competitive with respect to IMP | Borreliella burgdorferi | |
Mycophenolic acid | uncompetitive with respect to IMP and NAD+ | Borreliella burgdorferi | |
NAD+ | substrate inhibition at high concentration | Borreliella burgdorferi | |
thiazole-4-carboxamide adenine dinucleotide | uncompetitive with respect to IMP and NAD | Borreliella burgdorferi | |
xanthosine 5'-phosphate | competitive with respect to IMP | Borreliella burgdorferi |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Borreliella burgdorferi |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
additional information | - |
equilibrium sedimentation results suggest monomeric, dimeric and tetrameric forms and higher order aggregates | Borreliella burgdorferi |
43640 | - |
calculated from amino acid composition | Borreliella burgdorferi |
44000 | - |
SDS-PAGE | Borreliella burgdorferi |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
inosine 5'-phosphate + NAD+ + H2O | Borreliella burgdorferi | subdomain of the enzyme is not required for catalytic activity | xanthosine 5'-phosphate + NADH | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Borreliella burgdorferi | - |
- |
- |
Purification (Comment) | Organism |
---|---|
95% homogeneity | Borreliella burgdorferi |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.83 | - |
- |
Borreliella burgdorferi |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
inosine 5'-phosphate + NAD+ + H2O | subdomain of the enzyme is not required for catalytic activity | Borreliella burgdorferi | xanthosine 5'-phosphate + NADH | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0433 | - |
NAD+ | - |
Borreliella burgdorferi |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Borreliella burgdorferi |