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Literature summary for 1.1.1.202 extracted from

  • Hao, J.; Lin, R.; Zheng, Z.; Sun, Y.; Liu, D.
    3-Hydroxypropionaldehyde guided glycerol feeding strategy in aerobic 1,3-propanediol production by Klebsiella pneumoniae (2008), J. Ind. Microbiol. Biotechnol., 35, 1615-1624.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
glycerol
-
Klebsiella pneumoniae

Inhibitors

Inhibitors Comment Organism Structure
additional information when the concentration of 3-hydroxypropanal increases to a higher level in medium (ac 10 mmol/L), the activity of 1,3-propanediol oxidoreductase in cell decreases correspondingly, which leads to decrease of the 3-hydroxypropanal conversion rate, then the 3-hydroxypropanal concentration increasing is accelerated furthermore Klebsiella pneumoniae

Organism

Organism UniProt Comment Textmining
Klebsiella pneumoniae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxypropanal + NADH + H+ in the cell exponential growth phase, the reaction catalyzed by 1,3-propanediol oxidoreductase is the rate limiting step in 1,3-propanediol production Klebsiella pneumoniae propane-1,3-diol + NAD+
-
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Synonyms

Synonyms Comment Organism
1,3-propanediol oxidoreductase
-
Klebsiella pneumoniae
PDOR
-
Klebsiella pneumoniae

pH Range

pH Minimum pH Maximum Comment Organism
7 9
-
Klebsiella pneumoniae

Cofactor

Cofactor Comment Organism Structure
NADH
-
Klebsiella pneumoniae